RNF185 (NM_001135825) Human Mass Spec Standard
CAT＃: PH326760
RNF185 MS Standard C13 and N15-labeled recombinant protein (NP_001129297)
View other "RNF185" proteins (7)
|
Need it in bulk or customized? Get a free quote |
CNY 14250.00
Product images
Specifications
| Product Data | |
| Description | RNF185 MS Standard C13 and N15-labeled recombinant protein (NP_001129297) |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC226760 |
| Predicted MW | 14 kDa |
| Protein Sequence |
>RC226760 representing NM_001135825
Red=Cloning site Green=Tags(s) MASKGPSASASPENSSAGGPSGSSNGAGESGGQDSTFECNICLDTAKDAVISLCGHLFCWPCLHQGFQGF GFGDGGFQMSFGIGAFPFGIFATAFNINDGRPPPAVPGTPQYVDEQFLSRLFLFVALVIMFWLLIA TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Reference Data | |
| RefSeq | NP_001129297 |
| RefSeq ORF | 408 |
| Locus ID | 91445 |
| Cytogenetics | 22q12.2 |
| Summary | E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1 (PubMed:21931693). Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation (PubMed:27485036). Protects cells from ER stress-induced apoptosis (PubMed:27485036). Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway (PubMed:24019521). Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2 (PubMed:24019521).[UniProtKB/Swiss-Prot Function] |
| Protein Families | Druggable Genome, Transmembrane |
Documents
| FAQs |
| SDS |
Resources
| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC407689 | RNF185 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC427719 | RNF185 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC427720 | RNF185 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY407689 | Transient overexpression lysate of ring finger protein 185 (RNF185), transcript variant 1 |
CNY 3080.00 |
|
| LY427719 | Transient overexpression lysate of ring finger protein 185 (RNF185), transcript variant 2 |
CNY 3080.00 |
|
| LY427720 | Transient overexpression lysate of ring finger protein 185 (RNF185), transcript variant 3 |
CNY 3080.00 |
|
| TP326760 | Purified recombinant protein of Homo sapiens ring finger protein 185 (RNF185), transcript variant 3, 20 µg |
CNY 2900.00 |
Purified recombinant protein of Homo sapiens ring finger protein 185 (RNF185), transcript variant 3, 100 µg
