EIF5A (NM_001143762) Human Mass Spec Standard

CAT#: PH326664

EIF5A MS Standard C13 and N15-labeled recombinant protein (NP_001137234)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description EIF5A MS Standard C13 and N15-labeled recombinant protein (NP_001137234)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC226664
Predicted MW 16.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001137234
RefSeq Size 1340
RefSeq ORF 462
Synonyms eIF-4D; EIF-5A; EIF5A1; eIF5AI
Locus ID 1984
Cytogenetics 17p13.1
Summary mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.[UniProtKB/Swiss-Prot Function]
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