Mortality Factor 4 like 2 (MORF4L2) (NM_001142419) Human Mass Spec Standard

CAT#: PH326563

MORF4L2 MS Standard C13 and N15-labeled recombinant protein (NP_001135891)



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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description MORF4L2 MS Standard C13 and N15-labeled recombinant protein (NP_001135891)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC226563
Predicted MW 32.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001135891
RefSeq Size 1980
RefSeq ORF 864
Synonyms MORFL2; MRGX
Locus ID 9643
Cytogenetics Xq22.2
Summary Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.[UniProtKB/Swiss-Prot Function]
Protein Families Transcription Factors
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