IL36 gamma (IL36G) (NM_019618) Human Mass Spec Standard

Specifications

Product Data
Description	IL1F9 MS Standard C13 and N15-labeled recombinant protein (NP_062564)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC224784
Predicted MW	18.7 kDa
Protein Sequence	Sequence Link (showhide) >RC224784 protein sequence Red=Cloning site Green=Tags(s) MRGTPGDADGGGRAVYQSMCKPITGTINDLNQQVWTLQGQNLVAVPRSDSVTPVTVAVITCKYPEALEQG RGDPIYLGIQNPEMCLYCEKVGEQPTLQLKEQKIMDLYGQPEPVKPFLFYRAKTGRTSTLESVAFPDWFI ASSKRDQPIILTSELGKSYNTAFELNIND TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_062564
RefSeq Size	1212
RefSeq ORF	507
Synonyms	IL-1F9; IL-1H1; IL-1RP2; IL1E; IL1F9; IL1H1; IL1RP2
Locus ID	56300
Cytogenetics	2q14.1
Summary	The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, May 2019]
Protein Families	Druggable Genome, Secreted Protein

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