Neurogenin3 (NEUROG3) (NM_020999) Human Mass Spec Standard

Specifications

Product Data
Description	NEUROG3 MS Standard C13 and N15-labeled recombinant protein (NP_066279)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC224767
Predicted MW	22.9 kDa
Protein Sequence	Sequence Link (showhide) >RC224767 representing NM_020999 Red=Cloning site Green=Tags(s) MTPQPSGAPTVQVTRETERSFPRASEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSR PKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLR IADHSLYALEPPAPHCGELGSPGGSPGDWGSLYSPVSQAGSLSPAASLEERPGLLGATSSACLSPGSLAF SDFL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_066279
RefSeq Size	1167
RefSeq ORF	642
Synonyms	Atoh5; bHLHa7; Math4B; NGN-3; ngn3
Locus ID	50674
Cytogenetics	10q22.1
Summary	The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).[provided by RefSeq, May 2010]
Protein Families	ES Cell Differentiation/IPS
Protein Pathways	Maturity onset diabetes of the young

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