Dynamin 2 (DNM2) (NM_001005360) Human Mass Spec Standard

CAT#: PH323585

DNM2 MS Standard C13 and N15-labeled recombinant protein (NP_001005360)



  View other "Dynamin 2" proteins (9)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of dynamin 2 (DNM2), transcript variant 2
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Specifications

Product Data
Description DNM2 MS Standard C13 and N15-labeled recombinant protein (NP_001005360)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC223585
Predicted MW 98.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001005360
RefSeq Size 3684
RefSeq ORF 2610
Synonyms CMT2M; CMTDI1; CMTDIB; DI-CMTB; DYN2; DYNII; LCCS5
Locus ID 1785
Cytogenetics 19p13.2
Summary Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]
Protein Families Transcription Factors
Protein Pathways Endocytosis, Fc gamma R-mediated phagocytosis
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