Macrophage Scavenger Receptor I (MSR1) (NM_138716) Human Mass Spec Standard
CAT＃: PH323314
MSR1 MS Standard C13 and N15-labeled recombinant protein (NP_619730)
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CNY 19520.00
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CNY 3080.00
CNY 1999.00
CNY 2700.00
Specifications
| Product Data | |
| Description | MSR1 MS Standard C13 and N15-labeled recombinant protein (NP_619730) |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC223314 |
| Predicted MW | 42.8 kDa |
| Protein Sequence |
>RC223314 representing NM_138716
Red=Cloning site Green=Tags(s) MEQWDHFHNQQEDTDSCSESVKFDARSMTALLPPNPKNSPSLQEKLKSFKAALIALYLLVFAVLIPLIGI VAAQLLKWETKNCSVSSTNANDITQSLTGKGNDSEEEMRFQEVFMEHMSNMEKRIQHILDMEANLMDTEH FQNFSMTTDQRFNDILLQLSTLFSSVQGHGNAIDEISKSLISLNTTLLDLQLNIENLNGKIQENTFKQQE EISKLEERVYNVSAEIMAMKEEQVHLEQEIKGEVKVLNNITNDLRLKDWEHSQTLRNITLIQGPPGPPGE KGDRGPTGESGPRGFPGPIGPPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLSTGPIW LNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCTL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Reference Data | |
| RefSeq | NP_619730 |
| RefSeq Size | 3493 |
| RefSeq ORF | 1164 |
| Synonyms | CD204; phSR1; phSR2; SCARA1; SR-A; SR-AI; SR-AII; SR-AIII; SRA |
| Locus ID | 4481 |
| Cytogenetics | 8p22 |
| Summary | This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008] |
| Protein Families | Druggable Genome, Transmembrane |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC403366 | MSR1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
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| LC408527 | MSR1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC419319 | MSR1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY403366 | Transient overexpression lysate of macrophage scavenger receptor 1 (MSR1), transcript variant SR-AI |
CNY 3080.00 |
|
| LY408527 | Transient overexpression lysate of macrophage scavenger receptor 1 (MSR1), transcript variant SR-AIII |
CNY 3080.00 |
|
| LY419319 | Transient overexpression lysate of macrophage scavenger receptor 1 (MSR1), transcript variant SR-AII |
CNY 3080.00 |
|
| PH312931 | MSR1 MS Standard C13 and N15-labeled recombinant protein (NP_002436) |
CNY 19520.00 |
|
| TP312931 | Recombinant protein of human macrophage scavenger receptor 1 (MSR1), transcript variant SR-AII, 20 µg |
CNY 2900.00 |
|
| TP323314 | Recombinant protein of human macrophage scavenger receptor 1 (MSR1), transcript variant SR-AIII, 20 µg |
CNY 2900.00 |
|
| TP761290 | Purified recombinant protein of Human macrophage scavenger receptor 1 (MSR1), transcript variant SR-AI, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug |
CNY 2040.00 |
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