LCE3A (NM_178431) Human Mass Spec Standard

Specifications

Product Data
Description	LCE3A MS Standard C13 and N15-labeled recombinant protein (NP_848518)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC222176
Predicted MW	9 kDa
Protein Sequence	Sequence Link (showhide) >RC222176 representing NM_178431 Red=Cloning site Green=Tags(s) MSCQQNQQQCQPPPKCPAKSPAQCLPPASSSCAPSSGGCGPSSERSCCLSHHRCRRSHRCRCQSSNSCDR GSGQQGGSSSCGHSSAGCC TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_848518
RefSeq Size	270
RefSeq ORF	267
Synonyms	LEP13
Locus ID	353142
Cytogenetics	1q21.3
Summary	A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens (PubMed:28634035).[UniProtKB/Swiss-Prot Function]

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