SPANXB1 (NM_032461) Human Mass Spec Standard

Specifications

Product Data
Description	SPANXB1 MS Standard C13 and N15-labeled recombinant protein (NP_115850)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC221009
Predicted MW	11.8 kDa
Protein Sequence	Sequence Link (showhide) >RC221009 protein sequence Red=Cloning site Green=Tags(s) MGQQSSVRRLKRSVPCESNEANEANEANKTMPETPTGDSDPQPAPKKMKTSESSTILVVRYRRNVKRTSP EELVNDHARENRINPDQMEEEEFIEITTERPKK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_115850
RefSeq Size	469
RefSeq ORF	309
Synonyms	B1; CT11.2; SPANX-B; SPANXB; SPANXB2; SPANXF1; SPANXF2
Locus ID	728695
Cytogenetics	Xq27.1
Summary	Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular family member contains an additional 18 nucleotides in its coding region compared to the other family members in the same gene cluster. This family member is also subject to gene copy number variation. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. [provided by RefSeq, Apr 2014]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.