Complement factor 8 beta (C8B) (NM_000066) Human Mass Spec Standard

CAT#: PH319942

C8B MS Standard C13 and N15-labeled recombinant protein (NP_000057)



  View other "Complement factor 8 beta" proteins (3)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of complement component 8, beta polypeptide (C8B)
    • 100 ug

CNY 4,840.00


Rabbit Polyclonal Anti-C8B Antibody
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Description C8B MS Standard C13 and N15-labeled recombinant protein (NP_000057)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219942
Predicted MW 67 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000057
RefSeq Size 2178
RefSeq ORF 1773
Synonyms C82
Locus ID 732
Cytogenetics 1p32.2
Summary This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus
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