ACSL5 (NM_203380) Human Mass Spec Standard

CAT#: PH318932

ACSL5 MS Standard C13 and N15-labeled recombinant protein (NP_976314)



  View other "ACSL5" proteins (9)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description ACSL5 MS Standard C13 and N15-labeled recombinant protein (NP_976314)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218932
Predicted MW 82.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_976314
RefSeq Size 3399
RefSeq ORF 2220
Synonyms ACS2; ACS5; FACL5
Locus ID 51703
Cytogenetics 10q25.2
Summary The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Transmembrane
Protein Pathways Adipocytokine signaling pathway, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway
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