PROP1 (NM_006261) Human Mass Spec Standard

Specifications

Product Data
Description	PROP1 MS Standard C13 and N15-labeled recombinant protein (NP_006252)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC218746
Predicted MW	25 kDa
Protein Sequence	Sequence Link (showhide) >RC218746 protein sequence Red=Cloning site Green=Tags(s) MEAERRRQAEKPKKGRVGSSLLPERHPATGTPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQRGRPHSRR RHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQERSLLQPLAHLSP AAFSSFLPESTACPYSYAAPPPPVTCFPHPYSHALPSQPSTGGAFALSHQSEDWYPTLHPAPAGHLPCPP PPPMLPLSLEPSKSWN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006252
RefSeq Size	1464
RefSeq ORF	678
Synonyms	CPHD2; PROP-1
Locus ID	5626
Cytogenetics	5q35.3
Summary	This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone. [provided by RefSeq, Sep 2011]
Protein Families	Druggable Genome, Transcription Factors

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