TRAF3 (NM_003300) Human Mass Spec Standard

CAT#: PH318682

TRAF3 MS Standard C13 and N15-labeled recombinant protein (NP_003291)



  View other "TRAF3" proteins (5)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Anti-TRAF3 rabbit polyclonal antibody
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Transient overexpression lysate of TNF receptor-associated factor 3 (TRAF3), transcript variant 1
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Specifications

Product Data
Description TRAF3 MS Standard C13 and N15-labeled recombinant protein (NP_003291)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218682
Predicted MW 64.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_003291
RefSeq Size 7654
RefSeq ORF 1704
Synonyms CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1; RNF118
Locus ID 7187
Cytogenetics 14q32.32
Summary The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. The protein also plays a role in the regulation of antiviral response. Mutations in this are associated with Encephalopathy, acute, infection-induced, herpes-specific 5. [provided by RefSeq, Jul 2020]
Protein Families Druggable Genome
Protein Pathways Pathways in cancer, RIG-I-like receptor signaling pathway, Small cell lung cancer, Toll-like receptor signaling pathway
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