RAB3IP (NM_022456) Human Mass Spec Standard

CAT#: PH318153

RAB3IP MS Standard C13 and N15-labeled recombinant protein (NP_071901)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description RAB3IP MS Standard C13 and N15-labeled recombinant protein (NP_071901)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218153
Predicted MW 51.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_071901
RefSeq Size 1855
RefSeq ORF 1380
Synonyms RABIN3; RABIN8
Locus ID 117177
Cytogenetics 12q15
Summary Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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