C1orf80 (AIDA) (NM_022831) Human Mass Spec Standard

Specifications

Product Data
Description	AIDA MS Standard C13 and N15-labeled recombinant protein (NP_073742)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC217521
Predicted MW	35 kDa
Protein Sequence	Sequence Link (showhide) >RC217521 protein sequence Red=Cloning site Green=Tags(s) MSEVTRSLLQRWGASFRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCL ELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGA GAGSPDSFPARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVA SRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPT DFKRKKLQLLTKKPLYLHLHQTLHKE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_073742
RefSeq Size	3020
RefSeq ORF	918
Synonyms	C1orf80
Locus ID	64853
Cytogenetics	1q41
Summary	Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).[UniProtKB/Swiss-Prot Function]

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