NTH1 (NTHL1) (NM_002528) Human Mass Spec Standard

Specifications

Product Data
Description	NTHL1 MS Standard C13 and N15-labeled recombinant protein (NP_002519)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC214598
Predicted MW	34.2 kDa
Protein Sequence	Sequence Link (showhide) >RC214598 representing NM_002528 Red=Cloning site Green=Tags(s) MCSPQESGMTALSARMLTRSRSLGPGAGPRGCREEPGPLRRREAAAEARKSHSPVKRPRKAQRLRVAYEG SDSEKGEGAEPLKVPVWEPQDWQQQLVNIRAMRNKKDAPVDHLGTEHCYDSSAPPKVRRYQVLLSLMLSS QTKDQVTAGAMQRLRARGLTVDSILQTDDATLGKLIYPVGFWRSKVKYIKQTSAILQQHYGGDIPASVAE LVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIANRLRWTKKATKSPEETRAALEEWLPRELWHEING LLVGFGQQTCLPVHPRCHACLNQALCPAAQGL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002519
RefSeq Size	1097
RefSeq ORF	936
Synonyms	FAP3; hNTH1; NTH1; OCTS3
Locus ID	4913
Cytogenetics	16p13.3
Summary	The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity. [provided by RefSeq, Oct 2008]
Protein Families	Druggable Genome, Stem cell - Pluripotency
Protein Pathways	Base excision repair

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