EDDM3B (NM_022360) Human Mass Spec Standard

Specifications

Product Data
Description	EDDM3B MS Standard C13 and N15-labeled recombinant protein (NP_071755)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC213305
Predicted MW	17.6 kDa
Protein Sequence	Sequence Link (showhide) >RC213305 protein sequence Red=Cloning site Green=Tags(s) MASSVKIWGTLLALLCILCTLLVQSKEVSWREFMKQHYLSPSREFREYKCDVLMRENEALKDKSSHMFIY ISWYKIEHICTSDNWMDRFRNAYVWVQNPLKVLKCHQENSKNSYTESRSFNYIEFHCSMDGYVDSIEDLK MVEPIGN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_071755
RefSeq Size	897
RefSeq ORF	441
Synonyms	EP3B; FAM12B; HE3-BETA; HE3B; RAM2
Locus ID	64184
Cytogenetics	14q11.2
Summary	Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells. [provided by RefSeq, Jul 2008]
Protein Families	Secreted Protein, Transmembrane

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