TNFSF18 (NM_005092) Human Mass Spec Standard

Specifications

Product Data
Description	TNFSF18 MS Standard C13 and N15-labeled recombinant protein (NP_005083)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC210901
Predicted MW	20.31 kDa
Protein Sequence	Sequence Link (showhide) >RC210901 representing NM_005092 Red=Cloning site Green=Tags(s) MCLSHLENMPLSHSRTQGAQRSSWKLWLFCSIVMLLFLCSFSWLIFIFLQLETAKEPCMAKFGPLPSKWQ MASSEPPCVNKVSDWKLEILQNGLYLIYGQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTY ELHVGDTIDLIFNSEHQVLKNNTYWGIILLANPQFIS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005083
RefSeq Size	748
RefSeq ORF	531
Synonyms	AITRL; GITRL; hGITRL; TL6; TNLG2A
Locus ID	8995
Cytogenetics	1q25.1
Summary	The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction

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