DEFA6 (NM_001926) Human Mass Spec Standard

Specifications

Product Data
Description	DEFA6 MS Standard C13 and N15-labeled recombinant protein (NP_001917)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC210229
Predicted MW	11 kDa
Protein Sequence	Sequence Link (showhide) >RC210229 protein sequence Red=Cloning site Green=Tags(s) MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSSLRALGSTRAF TCHCRRSCYSTEYSYGTCTVMGINHRFCCL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001917
RefSeq Size	479
RefSeq ORF	300
Synonyms	DEF6; HD-6
Locus ID	1671
Cytogenetics	8p23.1
Summary	Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq, Oct 2014]
Protein Families	Secreted Protein

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