TYW3 (NM_138467) Human Mass Spec Standard

Specifications

Product Data
Description	TYW3 MS Standard C13 and N15-labeled recombinant protein (NP_612476)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC210021
Predicted MW	29.8 kDa
Protein Sequence	Sequence Link (showhide) >RC210021 protein sequence Red=Cloning site Green=Tags(s) MDRSAEFRKWKAQCLSKADLSRKGSVDEDVVELVQFLNMRDQFFTTSSCAGRILLLDRGINGFEVQKQNC CWLLVTHKLCVKDDVIVALKKANGDATLKFEPFVLHVQCRQLQDAQILHSMAIDSGFRNSGITVGKRGKT MLVVRSTHGLEVPLSHKGKLMVTEEYIDFLLNVANQKMEENKKRIERFYNCLQHALERETMTNLHPKIKE KNNSSYIHKKKRNPEKTRAQCITKESDEELENDDDDDLGINVTIFPEDY TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_612476
RefSeq Size	3448
RefSeq ORF	777
Synonyms	C1orf171
Locus ID	127253
Cytogenetics	1p31.1
Summary	Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]

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