S100A12 (NM_005621) Human Mass Spec Standard

Specifications

Product Data
Description	S100A12 MS Standard C13 and N15-labeled recombinant protein (NP_005612)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC210002
Predicted MW	10.6 kDa
Protein Sequence	Sequence Link (showhide) >RC210002 protein sequence Red=Cloning site Green=Tags(s) MTKLEEHLEGIVNIFHQYSVRKGHFDTLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVD FQEFISLVAIALKAAHYHTHKE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005612
RefSeq Size	466
RefSeq ORF	276
Synonyms	CAAF1; CAGC; CGRP; ENRAGE; MRP-6; MRP6; p6
Locus ID	6283
Cytogenetics	1q21.3
Summary	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity. [provided by RefSeq, Nov 2014]

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