Adenine Nucleotide Translocator 2 (SLC25A5) (NM_001152) Human Mass Spec Standard

Specifications

Product Data
Description	SLC25A5 MS Standard C13 and N15-labeled recombinant protein (NP_001143)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC208949
Predicted MW	32.9 kDa
Protein Sequence	Sequence Link (showhide) >RC208949 protein sequence Red=Cloning site Green=Tags(s) MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSF WRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTR LAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHI VISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR GMGGAFVLVLYDEIKKYT TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001143
RefSeq Size	1351
RefSeq ORF	894
Synonyms	2F1; AAC2; ANT2; T2; T3
Locus ID	292
Cytogenetics	Xq24
Summary	This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Calcium signaling pathway, Huntington's disease, Parkinson's disease

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