AGR3 (NM_176813) Human Mass Spec Standard

Specifications

Product Data
Description	AGR3 MS Standard C13 and N15-labeled recombinant protein (NP_789783)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC208897
Predicted MW	19.2 kDa
Protein Sequence	Sequence Link (showhide) >RC208897 protein sequence Red=Cloning site Green=Tags(s) MMLHSALGLCLLLVTVSSNLAIAIKKEKRPPQTLSRGWGDDITWVQTYEEGLFYAQKSKKPLMVIHHLED CQYSQALKKVFAQNEEIQEMAQNKFIMLNLMHETTDKNLSPDGQYVPRIMFVDPSLTVRADIAGRYSNRL YTYEPRDLPLLIENMKKALRLIQSEL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_789783
RefSeq Size	763
RefSeq ORF	498
Synonyms	AG-3; AG3; BCMP11; hAG-3; HAG3; PDIA18
Locus ID	155465
Cytogenetics	7p21.1
Summary	This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016]
Protein Families	Secreted Protein

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