Spasmolytic Polypeptide (TFF2) (NM_005423) Human Mass Spec Standard

Specifications

Product Data
Description	TFF2 MS Standard C13 and N15-labeled recombinant protein (NP_005414)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC207571
Predicted MW	14.3 kDa
Protein Sequence	Sequence Link (showhide) >RC207571 protein sequence Red=Cloning site Green=Tags(s) MGRRDAQLLAALLVLGLCALAGSEKPSPCQCSRLSPHNRTNCGFPGITSDQCFDNGCCFDSSVTGVPWCF HPLPKQESDQCVMEVSDRRNCGYPGISPEECASRKCCFSNFIFEVPWCFFPKSVEDCHY TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005414
RefSeq Size	717
RefSeq ORF	387
Synonyms	SML1; SP
Locus ID	7032
Cytogenetics	21q22.3
Summary	Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Secreted Protein

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