Glutathione Peroxidase 7 (GPX7) (NM_015696) Human Mass Spec Standard

Specifications

Product Data
Description	GPX7 MS Standard C13 and N15-labeled recombinant protein (NP_056511)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC207428
Predicted MW	21 kDa
Protein Sequence	Sequence Link (showhide) >RC207428 protein sequence Red=Cloning site Green=Tags(s) MVAATVAAAWLLLWAAACAQQEQDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQL QRDLGPHHFNVLAFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAVTGTGAHPAFKYLAQTSGKEP TWNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRKLILLKREDL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_056511
RefSeq Size	1246
RefSeq ORF	561
Synonyms	CL683; GPx-7; GPX6; GSHPx-7; NPGPx
Locus ID	2882
Cytogenetics	1p32.3
Summary	It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Arachidonic acid metabolism, Glutathione metabolism

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