RAB39 (RAB39A) (NM_017516) Human Mass Spec Standard

Specifications

Product Data
Description	RAB39 MS Standard C13 and N15-labeled recombinant protein (NP_059986)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC207062
Predicted MW	25 kDa
Protein Sequence	Sequence Link (showhide) >RC207062 protein sequence Red=Cloning site Green=Tags(s) METIWIYQFRLIVIGDSTVGKSCLLHRFTQGRFPGLRSPACDPTVGVDFFSRLLEIEPGKRIKLQLWDTA GQERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEEAKMYVQPFRIVFLLVGHKCDLASQRQVTRE EAEKLSADCGMKYIETSAKDATNVEESFTILTRDIYELIKKGEICIQDGWEGVKSGFVPNTVHSSEEAVK PRKECFC TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_059986
RefSeq Size	1845
RefSeq ORF	651
Synonyms	RAB39
Locus ID	54734
Cytogenetics	11q22.3
Summary	Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Plays a role in the fusion of phagosomes with lysosomes. Negatively regulates LPS-induced autophagosome formation in macrophages possibly by implicating PI3K (PubMed:24349490). May be involved in multiple neurite formation (By similarity).[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome

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