DUSP28 (NM_001033575) Human Mass Spec Standard

Specifications

Product Data
Description	DUSP28 MS Standard C13 and N15-labeled recombinant protein (NP_001028747)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC206912
Predicted MW	18.3 kDa
Protein Sequence	Sequence Link (showhide) >RC206912 protein sequence Red=Cloning site Green=Tags(s) MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPV FDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVA EPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001028747
RefSeq Size	1555
RefSeq ORF	528
Synonyms	DUSP26; VHP
Locus ID	285193
Cytogenetics	2q37.3
Summary	Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate (in vitro) (PubMed:24531476, PubMed:29121083). Has almost no detectable activity with phosphotyrosine, even less activity with phosphothreonine and displays complete lack of activity with phosphoserine (PubMed:29121083). The poor activity with phosphotyrosine may be due to steric hindrance by bulky amino acid sidechains that obstruct access to the active site (PubMed:29121083).[UniProtKB/Swiss-Prot Function]

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