PACSIN1 (NM_020804) Human Mass Spec Standard

CAT#: PH306626

PACSIN1 MS Standard C13 and N15-labeled recombinant protein (NP_065855)



  View other "PACSIN1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of protein kinase C and casein kinase substrate in neurons 1 (PACSIN1)
    • 100 ug

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Goat Polyclonal Antibody against PACSIN1
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Specifications

Product Data
Description PACSIN1 MS Standard C13 and N15-labeled recombinant protein (NP_065855)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206626
Predicted MW 50.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_065855
RefSeq Size 4282
RefSeq ORF 1332
Synonyms SDPI
Locus ID 29993
Cytogenetics 6p21.31
Summary Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT; this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization. Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex. Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length. Required for normal synaptic vesicle endocytosis; this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission (By similarity). Binds to membranes via its F-BAR domain and mediates membrane tubulation.[UniProtKB/Swiss-Prot Function]
Protein Families Druggable Genome
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