PHPT1 (NM_014172) Human Mass Spec Standard

Specifications

Product Data
Description	PHPT1 MS Standard C13 and N15-labeled recombinant protein (NP_054891)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC205124
Predicted MW	13.8 kDa
Protein Sequence	Sequence Link (showhide) >RC205124 protein sequence Red=Cloning site Green=Tags(s) MAVADLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVRGYKWAEYHADIYDKVSGDMQKQGCD CECLGGGRISHQSQDKKIHVYGYSMAYGPAQHAISTEKIKAKYPDYEVTWANDGY TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_054891
RefSeq Size	1199
RefSeq ORF	375
Synonyms	CGI-202; HEL-S-132P; HSPC141; PHP; PHP14
Locus ID	29085
Cytogenetics	9q34.3
Summary	This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Protein Families	Druggable Genome
Protein Pathways	Fructose and mannose metabolism, Metabolic pathways, Riboflavin metabolism, Thiamine metabolism

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