MIF (NM_002415) Human Mass Spec Standard

Specifications

Product Data
Description	MIF MS Standard C13 and N15-labeled recombinant protein (NP_002406)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC205106
Predicted MW	12.5 kDa
Protein Sequence	Sequence Link (showhide) >RC205106 protein sequence Red=Cloning site Green=Tags(s) MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGG AQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002406
RefSeq Size	561
RefSeq ORF	345
Synonyms	GIF; GLIF; MMIF
Locus ID	4282
Cytogenetics	22q11.23
Summary	This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome
Protein Pathways	Phenylalanine metabolism, Tyrosine metabolism

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