LAGE3 (NM_006014) Human Mass Spec Standard

Specifications

Product Data
Description	LAGE3 MS Standard C13 and N15-labeled recombinant protein (NP_006005)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204863
Predicted MW	14.8 kDa
Protein Sequence	Sequence Link (showhide) >RC204863 protein sequence Red=Cloning site Green=Tags(s) MRDADADAGGGADGGDGRGGHSCRGGVDTAAAPAGGAPPAHAPGPGRDAASAARGSRMRPHIFTLSVPFP TPLEAEIAHGSLAPDAEPHQRVVGKDLTVSGRILVVRWKAEDCRLLRISVINFLDQLSLVVRTMQRFGPP VSR TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006005
RefSeq Size	964
RefSeq ORF	429
Synonyms	CVG5; DXS9879E; DXS9951E; ESO3; GAMOS2; ITBA2; Pcc1
Locus ID	8270
Cytogenetics	Xq28
Summary	This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9. [provided by RefSeq, Jul 2008]

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