RRAS2 (NM_012250) Human Mass Spec Standard

Specifications

Product Data
Description	RRAS2 MS Standard C13 and N15-labeled recombinant protein (NP_036382)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204591
Predicted MW	23.4 kDa
Protein Sequence	Sequence Link (showhide) >RC204591 protein sequence Red=Cloning site Green=Tags(s) MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTA GQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQE EGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQEQECPPSPEPTRKEKDKKGCHCVIF SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_036382
RefSeq Size	2360
RefSeq ORF	612
Synonyms	NS12; TC21
Locus ID	22800
Cytogenetics	11p15.2
Summary	This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
Protein Families	Druggable Genome
Protein Pathways	MAPK signaling pathway, Regulation of actin cytoskeleton, Tight junction

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