GI24 (C10orf54) (NM_022153) Human Mass Spec Standard

Specifications

Product Data
Description	C10orf54 MS Standard C13 and N15-labeled recombinant protein (NP_071436)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204547
Predicted MW	33.9 kDa
Protein Sequence	Sequence Link (showhide) >RC204547 protein sequence Red=Cloning site Green=Tags(s) MGVPTALEAGSWRWGSLLFALFLAASLGPVAAFKVATPYSLYVCPEGQNVTLTCRLLGPVDKGHDVTFYK TWYRSSRGEVQTCSERRPIRNLTFQDLHLHHGGHQAANTSHDLAQRHGLESASDHHGNFSITMRNLTLLD SGLYCCLVVEIRHHHSEHRVHGAMELQVQTGKDAPSNCVVYPSSSQESENITAAALATGACIVGILCLPL ILLLVYKQRQAASNRRAQELVRMDSNIQGIENPGFEASPPAQGIPEAKVRHPLSYVAQRQPSESGRHLLS EPSTPLSPPGPGDVFFPSLDPVPDSPNFEVI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_071436
RefSeq Size	4774
RefSeq ORF	933
Synonyms	B7-H5; B7H5; C10orf54; DD1alpha; Dies1; GI24; PD-1H; PP2135; SISP1; VISTA
Locus ID	64115
Cytogenetics	10q22.1
Summary	Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation (PubMed:20666777).[UniProtKB/Swiss-Prot Function]
Protein Families	Transmembrane

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