GNLY (NM_006433) Human Mass Spec Standard

Specifications

Product Data
Description	GNLY MS Standard C13 and N15-labeled recombinant protein (NP_006424)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204321
Predicted MW	16.4 kDa
Protein Sequence	Sequence Link (showhide) >RC204321 protein sequence Red=Cloning site Green=Tags(s) MATWALLLLAAMLLGNPGLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCL TIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDLRLCIP STGPL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006424
RefSeq Size	751
RefSeq ORF	435
Synonyms	D2S69E; LAG-2; LAG2; NKG5; TLA519
Locus ID	10578
Cytogenetics	2p11.2
Summary	The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Protein Families	Secreted Protein

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