14-3-3 sigma (SFN) (NM_006142) Human Mass Spec Standard

Specifications

Product Data
Description	SFN MS Standard C13 and N15-labeled recombinant protein (NP_006133)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204045
Predicted MW	27.8 kDa
Protein Sequence	Sequence Link (showhide) >RC204045 protein sequence Red=Cloning site Green=Tags(s) MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSN EEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDK KRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSE DSYKDSTLIMQLLRDNLTLWTADNAGEEGGEAPQEPQS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006133
RefSeq Size	1336
RefSeq ORF	744
Synonyms	YWHAS
Locus ID	2810
Cytogenetics	1p36.11
Summary	This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis. [provided by RefSeq, Aug 2017]
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Cell cycle, p53 signaling pathway

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