PLEKHF2 (NM_024613) Human Mass Spec Standard

Specifications

Product Data
Description	PLEKHF2 MS Standard C13 and N15-labeled recombinant protein (NP_078889)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203964
Predicted MW	27.8 kDa
Protein Sequence	Sequence Link (showhide) >RC203964 protein sequence Red=Cloning site Green=Tags(s) MVDRLANSEANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQ KKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSGKT PSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCYDL LSAGDMATCQPARSDSYSQSLKSPLNDMSDDDDDDDSSD TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_078889
RefSeq Size	2977
RefSeq ORF	747
Synonyms	EAPF; PHAFIN2; ZFYVE18
Locus ID	79666
Cytogenetics	8q22.1
Summary	May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467).[UniProtKB/Swiss-Prot Function]

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