Nucleophosmin (NPM1) (NM_199185) Human Mass Spec Standard

CAT#: PH303841

NPM1 MS Standard C13 and N15-labeled recombinant protein (NP_954654)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description NPM1 MS Standard C13 and N15-labeled recombinant protein (NP_954654)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203841
Predicted MW 29.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_954654
RefSeq Size 1362
RefSeq ORF 795
Synonyms B23; NPM
Locus ID 4869
Cytogenetics 5q35.1
Summary The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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