Angiotensinogen (AGT) (NM_000029) Human Mass Spec Standard
CAT#: PH303768
AGT MS Standard C13 and N15-labeled recombinant protein (NP_000020)
View other "Angiotensinogen" proteins (4)
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CNY 19,520.00
Specifications
Product Data | |
Description | AGT MS Standard C13 and N15-labeled recombinant protein (NP_000020) |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC203768 |
Predicted MW | 53.1 kDa |
Protein Sequence |
>RC203768 protein sequence
Red=Cloning site Green=Tags(s) MRKRAPQSEMAPAGVSLRATILCLLAWAGLAAGDRVYIHPFHLVIHNESTCEQLAKANAGKPKDPTFIPA PIQAKTSPVDEKALQDQLVLVAAKLDTEDKLRAAMVGMLANFLGFRIYGMHSELWGVVHGATVLSPTAVF GTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVG VFTAPGLHLKQPFVQGLALYTPVVLPRSLDFTELDVAAEKIDRFMQAVTGWKTGCSLTGASVDSTLAFNT YVHFQGKMKGFSLLAEPQEFWVDNSTSVSVPMLSGMGTFQHWSDIQDNFSVTQVSFTESACLLLIQPHYA SDLDKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLSNDRIR VGEVLNSIFFELEADEREPTESTQQLNKPEVLEVTLNRPFLFAVYDQSATALHFLGRVANPLSTA TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Reference Data | |
RefSeq | NP_000020 |
RefSeq Size | 2587 |
RefSeq ORF | 1455 |
Synonyms | ANHU; hFLT1; SERPINA8 |
Locus ID | 183 |
Cytogenetics | 1q42.2 |
Summary | The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure, body fluid and electrolyte homeostasis, and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Nov 2019] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Renin-angiotensin system |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400005 | AGT HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY400005 | Transient overexpression lysate of angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT) |
CNY 3,080.00 |
|
TP303768 | Recombinant protein of human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT), 20 µg |
CNY 2,900.00 |
|
TP721058 | Purified recombinant protein of Human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT) |
CNY 3,140.00 |
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