NMRAL1 (NM_020677) Human Mass Spec Standard

Specifications

Product Data
Description	NMRAL1 MS Standard C13 and N15-labeled recombinant protein (NP_065728)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203602
Predicted MW	33.3 kDa
Protein Sequence	Sequence Link (showhide) >RC203602 protein sequence Red=Cloning site Green=Tags(s) MVDKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKELRLQGAEVVQGDQDDQVIMELALN GAYATFIVTNYWESCSQEQEVKQGKLLADLARRLGLHYVVYSGLENIKKLTAGRLAAAHFDGKGEVEEYF RDIGVPMTSVRLPCYFENLLSHFLPQKAPDGKSYLLSLPTGDVPMDGMSVSDLGPVVLSLLKMPEKYVGQ NIGLSTCRHTAEEYAALLTKHTRKVVHDAKMTPEDYEKLGFPGARDLANMFRFYALRPDRDIELTLRLNP KALTLDQWLEQHKGDFNLL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_065728
RefSeq Size	1401
RefSeq ORF	897
Synonyms	HSCARG; SDR48A1
Locus ID	57407
Cytogenetics	16p13.3
Summary	This gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF-kappaB in a ubiquitylation-dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]

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