CDC34 (NM_004359) Human Mass Spec Standard

Specifications

Product Data
Description	CDC34 MS Standard C13 and N15-labeled recombinant protein (NP_004350)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203517
Predicted MW	26.6 kDa
Protein Sequence	Sequence Link (showhide) >RC203517 representing NM_004359 Red=Cloning site Green=Tags(s) MARPLVPSSQKALLLELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPY SPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPA NVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVKTKAPAPDEGSDLFYDDY YEDGEVEEEADSCFGDDEDDSGTEES TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004350
RefSeq Size	1462
RefSeq ORF	708
Synonyms	E2-CDC34; UBC3; UBCH3; UBE2R1
Locus ID	997
Cytogenetics	19p13.3
Summary	The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication. [provided by RefSeq, Jul 2008]
Protein Pathways	Ubiquitin mediated proteolysis

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