CAPNS1 (NM_001003962) Human Mass Spec Standard

CAT#: PH303233

CAPNS1 MS Standard C13 and N15-labeled recombinant protein (NP_001003962)



  View other "CAPNS1" proteins (5)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of calpain, small subunit 1 (CAPNS1), transcript variant 1
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Specifications

Product Data
Description CAPNS1 MS Standard C13 and N15-labeled recombinant protein (NP_001003962)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203233
Predicted MW 28.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001003962
RefSeq Size 1489
RefSeq ORF 804
Synonyms CALPAIN4; CANP; CANPS; CAPN4; CDPS; CSS1
Locus ID 826
Cytogenetics 19q13.12
Summary This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Protein Families Druggable Genome, Protease
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