FAM162A (NM_014367) Human Mass Spec Standard

Specifications

Product Data
Description	FAM162A MS Standard C13 and N15-labeled recombinant protein (NP_055182)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203056
Predicted MW	17.4 kDa
Protein Sequence	Sequence Link (showhide) >RC203056 protein sequence Red=Cloning site Green=Tags(s) MGSLSGLRLAAGSCFRLCERDVSSSLRLTRSSDLKRINGFCTKPQESPGVPSRTYNRVPLHKPTDWQKKI LIWSGRFKKEDEIPETVSLEMLDAAKNKMRVKISYLMIALTVVGCIFMVIEGKKAAQRHETLTSLNLEKK ARLKEEAAMKAKTE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_055182
RefSeq Size	838
RefSeq ORF	462
Synonyms	C3orf28; E2IG5; HGTD-P
Locus ID	26355
Cytogenetics	3q21.1
Summary	Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly.[UniProtKB/Swiss-Prot Function]
Protein Families	Transmembrane

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