DERL2 (NM_016041) Human Mass Spec Standard

Specifications

Product Data
Description	DERL2 MS Standard C13 and N15-labeled recombinant protein (NP_057125)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203046
Predicted MW	27.6 kDa
Protein Sequence	Sequence Link (showhide) >RC203046 protein sequence Red=Cloning site Green=Tags(s) MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFN FLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVR MNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVFPNQPGGIRILKTPSILKAIFD TPDEDPNYNPLPEERPGGFAWGEGQRLGG TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_057125
RefSeq Size	1156
RefSeq ORF	717
Synonyms	CGI-101; derlin-2; DERtrin-2; F-LAN-1; F-LANa; FLANa
Locus ID	51009
Cytogenetics	17p13.2
Summary	Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM, Mar 2008]
Protein Families	Transmembrane

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