CCDC115 (NM_032357) Human Mass Spec Standard

Specifications

Product Data
Description	CCDC115 MS Standard C13 and N15-labeled recombinant protein (NP_115733)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202967
Predicted MW	19.8 kDa
Protein Sequence	Sequence Link (showhide) >RC202967 protein sequence Red=Cloning site Green=Tags(s) MAALDLRAELDSLVLQLLGDLEELEGKRTVLNARVEEGWLSLAKARYAMGAKSVGPLQYASHMEPQVCLH ASEAQEGLQKFKVVRAGVHAPEEVGPREAGLRRRKGPTKTPEPESSEAPQDPLNWFGILVPHSLRQAQAS FRDGLQLAADIASLQNRIDWGRSQLRGLQEKLKQLEPGAA TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_115733
RefSeq Size	2000
RefSeq ORF	540
Synonyms	ccp1; CDG2O
Locus ID	84317
Cytogenetics	2q21.1
Summary	The protein encoded by this gene has been observed to localize to the endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC) and coat protein complex I (COPI) vesicles in some human cells. The encoded protein shares some homology with the yeast V-ATPase assembly factor Vma22p, and the orthologous protein in mouse promotes cell proliferation and suppresses cell death. Defects in this gene are a cause of congenital disorder of glycosylation, type IIo in humans. [provided by RefSeq, Mar 2016]

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