Pet1 (FEV) (NM_017521) Human Mass Spec Standard

Specifications

Product Data
Description	FEV MS Standard C13 and N15-labeled recombinant protein (NP_059991)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202917
Predicted MW	24.8 kDa
Protein Sequence	Sequence Link (showhide) RC202917
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_059991
RefSeq Size	1901
RefSeq ORF	714
Synonyms	HSRNAFEV; PET-1
Locus ID	54738
Cytogenetics	2q35
Summary	This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Transcription Factors

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