LXN (NM_020169) Human Mass Spec Standard

Specifications

Product Data
Description	LXN MS Standard C13 and N15-labeled recombinant protein (NP_064554)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202769
Predicted MW	25.8 kDa
Protein Sequence	Sequence Link (showhide) >RC202769 protein sequence Red=Cloning site Green=Tags(s) MEIPPTNYPASRAALVAQNYINYQQGTPHRVFEVQKVKQASMEDIPGRGHKYRLKFAVEEIIQKQVKVNC TAEVLYPSTGQETAPEVNFTFEGETGKNPDEEDNTFYQRLKSMKEPLEAQNIPDNFGNVSPEMTLVLHLA WVACGYIIWQNSTEDTWYKMVKIQTVKQVQRNDDFIELDYTILLHNIASQEIIPWQMQVLWHPQYGTKVK HNSRLPKEVQLE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_064554
RefSeq Size	1132
RefSeq ORF	666
Synonyms	ECI; TCI
Locus ID	56925
Cytogenetics	3q25.32
Summary	This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. The encoded protein, latexin, downregulates the population size of hematopoietic stem cells. This protein is found to be downregulated in cancer cells because of promoter hypermethylation. [provided by RefSeq, Jul 2020]

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