DIMT1L (DIMT1) (NM_014473) Human Mass Spec Standard

Specifications

Product Data
Description	DIMT1L MS Standard C13 and N15-labeled recombinant protein (NP_055288)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202326
Predicted MW	35.2 kDa
Protein Sequence	Sequence Link (showhide) >RC202326 protein sequence Red=Cloning site Green=Tags(s) MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNM TVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFK LLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIE PKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQIL TSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_055288
RefSeq Size	1557
RefSeq ORF	939
Synonyms	DIM1; DIMT1L; HSA9761; HUSSY5
Locus ID	27292
Cytogenetics	5q12.1
Summary	The protein encoded by this gene is a methyltransferase that is responsible for dimethylation of adjacent adenosines near the 18S rRNA decoding site. The encoded protein is essential for ribosome biogenesis, although its catalytic activity is not involved in the process. The yeast ortholog of this protein functions in the cytoplasm while this protein functions in the nucleus. [provided by RefSeq, Jan 2017]
Protein Families	Druggable Genome

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