GSTA4 (NM_001512) Human Mass Spec Standard

CAT#: PH302130

GSTA4 MS Standard C13 and N15-labeled recombinant protein (NP_001503)



  View other "GSTA4" proteins (4)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description GSTA4 MS Standard C13 and N15-labeled recombinant protein (NP_001503)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202130
Predicted MW 25.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001503
RefSeq Size 1352
RefSeq ORF 666
Synonyms GSTA4-4; GTA4
Locus ID 2941
Cytogenetics 6p12.2
Summary Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis. [provided by RefSeq, Jul 2008]
Protein Pathways Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450
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