MSX2 (NM_002449) Human Mass Spec Standard

Specifications

Product Data
Description	MSX2 MS Standard C13 and N15-labeled recombinant protein (NP_002440)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202056
Predicted MW	28.9 kDa
Protein Sequence	Sequence Link (showhide) >RC202056 protein sequence Red=Cloning site Green=Tags(s) MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEASPLPAESA SAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPGRYSPPPRHTSPTTCTLRKHK TNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKM AAKPMLPSSFSLPFPISSPLQAASIYGASYPFHRPVLPIPPVGLYATPVGYGMYHLS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002440
RefSeq Size	2224
RefSeq ORF	801
Synonyms	CRS2; FPP; HOX8; MSH; PFM; PFM1
Locus ID	4488
Cytogenetics	5q35.2
Summary	This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Transcription Factors

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