CLN6 (NM_017882) Human Mass Spec Standard

Specifications

Product Data
Description	CLN6 MS Standard C13 and N15-labeled recombinant protein (NP_060352)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201904
Predicted MW	35.9 kDa
Protein Sequence	Sequence Link (showhide) >RC201904 protein sequence Red=Cloning site Green=Tags(s) MEATRRRQHLGATGGPGAQLGASFLQARHGSVSADEAARTAPFHLDLWFYFTLQNWVLDFGRPIAMLVFP LEWFPLNKPSVGDYFHMAYNVITPFLLLKLIERSPRTLPRSITYVSIIIFIMGASIHLVGDSVNHRLLFS GYQHHLSVRENPIIKNLKPETLIDSFELLYYYDEYLGHCMWYIPFFLILFMYFSGCFTASKAESLIPGPA LLLVAPSGLYYWYLVTEGQIFILFIFTFFAMLALVLHQKRKRLFLDSNGLFLFSSFALTLLLVALWVAWL WNDPVLRKKYPGVIYVPEPWAFYTLHVSSRH TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_060352
RefSeq Size	2258
RefSeq ORF	933
Synonyms	CLN4A; HsT18960; nclf
Locus ID	54982
Cytogenetics	15q23
Summary	This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. [provided by RefSeq, Oct 2008]
Protein Families	Transmembrane

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